Erdafitinib - Janssen Pharmaceutica

Drug Profile

Erdafitinib - Janssen Pharmaceutica

Alternative Names: G-024; JNJ-42756493; JNJ-493

Latest Information Update: 28 Jul 2018

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At a glance

  • Originator Astex Therapeutics
  • Developer Genentech; Janssen Pharmaceutica; Janssen Research & Development; Multiple Myeloma Research Consortium; National Cancer Institute (USA); University Health Network of Toronto; Vanderbilt-Ingram Cancer Center
  • Class Antineoplastics; Diamines; Pyrazoles; Quinoxalines; Small molecules
  • Mechanism of Action Fibroblast growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Urogenital cancer
  • Phase II Cholangiocarcinoma; Gastric cancer; Multiple myeloma; Non-Hodgkin's lymphoma; Non-small cell lung cancer; Oesophageal cancer; Solid tumours
  • Phase I/II Hepatocellular carcinoma; Lymphoma
  • Phase I Breast cancer
  • No development reported Cancer

Most Recent Events

  • 28 Jul 2018 No recent reports of development identified for phase-I development in Cancer(In volunteers) in Belgium (PO, Capsule)
  • 28 Jul 2018 No recent reports of development identified for phase-I development in Cancer(In volunteers) in Belgium (PO, Liquid)
  • 28 Jul 2018 No recent reports of development identified for phase-I development in Lymphoma(Late-stage disease, Second-line therapy or greater) in France (PO)
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