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PF 6425090

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Drug Profile

PF 6425090

Alternative Names: Clostridium difficile vaccine - Pfizer; PF-06425090; PF-6425090; Toxoid-based Clostridium difficile vaccine - Pfizer

Latest Information Update: 10 Sep 2025

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At a glance

  • Originator Pfizer
  • Class Bacterial vaccines; Subunit vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Clostridium difficile infections

Most Recent Events

  • 29 Apr 2025 Discontinued - Phase-III for Clostridium difficile infections (In the elderly, Prevention) in USA (IM)
  • 29 Apr 2025 Discontinued - Phase-III for Clostridium difficile infections (Prevention) in Sweden, Taiwan, Spain, United Kingdom, Argentina, Slovakia, Portugal, Poland, Peru, South Korea, Hungary, Germany, France, Finland, Czech Republic, Chile, Colombia, Bulgaria, Belgium, Canada, Australia, Japan, USA (IM)
  • 03 Mar 2022 Pfizer completes the phase III CLOVER trial in Clostridium difficile infection (Prevention) in USA, Japan, Canada, Argentina, Australia, Belgium, Bulgaria, Chile, Colombia, Czech Republic, Finland, France, Germany, Hungary, South Korea, Peru, Poland, Portugal, Slovakia, Spain, Sweden, Taiwan and United Kingdom (IM, Injection) (EudraCT2016-003866-14) (NCT03090191)

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