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Drug Profile


Alternative Names: LPMX-1; LPMX-2; PL-MLP; Promitil

Latest Information Update: 20 Apr 2019

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At a glance

  • Originator Hebrew University of Jerusalem
  • Developer Lipomedix Pharmaceuticals
  • Class Antineoplastics; Cytostatic antibiotics
  • Mechanism of Action Alkylating agents; DNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Colorectal cancer; Solid tumours
  • Preclinical Bladder cancer

Most Recent Events

  • 29 Mar 2019 Efficacy and pharmacokinetics data from a phase I trial in Solid tumours presented at the 110th Annual Meeting of the American Association for Cancer Research (AACR-2019)
  • 03 Jan 2019 Lipomedix Pharmaceuticals initiates enrolment in a phase I trial for Solid tumours (Late-stage disease, Second-line therapy or greater) in Israel (NCT03823989)
  • 23 Jul 2018 PL MLP is still in phase I trials for Solid-tumours (Late-stage disease) in Israel
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