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PL MLP

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Drug Profile

PL MLP

Alternative Names: LPMX-1; LPMX-2; PL-MLP; Promitil

Latest Information Update: 28 Jul 2026

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At a glance

  • Originator Hebrew University of Jerusalem
  • Developer Lipomedix Pharmaceuticals
  • Class Antineoplastics; Carbamates; Cytostatic antibiotics; Disulfides; Mitomycins
  • Mechanism of Action Alkylating agents; DNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Adenocarcinoma; Ovarian cancer
  • No development reported Bladder cancer; Colorectal cancer; Gastrointestinal cancer

Most Recent Events

  • 28 Jul 2026 No recent reports of development identified for phase-I development in Colorectal-cancer(Combination therapy, Metastatic disease, Second-line therapy or greater) in Israel (IV, Infusion)
  • 28 Jul 2026 No recent reports of development identified for preclinical development in Bladder-cancer in Israel (Intravesicular, Liquid)
  • 02 Jan 2026 Lipomedix Pharmaceuticals terminates phase II trial in Adenocarcinoma (Inoperable/Unresectable, Late-stage disease, Second-line therapy or greater, Metastatic disease) in Israel (IV) due to sponsor decision(NCT06478862)

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