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Paridiprubart - Edesa Biotech

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Drug Profile

Paridiprubart - Edesa Biotech

Alternative Names: EB 05; EB-07; NI-0101

Latest Information Update: 05 Nov 2025

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At a glance

  • Originator NovImmune SA
  • Developer Edesa Biotech; Light Chain Bioscience
  • Class Anti-inflammatories; Antirheumatics; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Toll-like receptor 4 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III SARS-CoV-2 acute respiratory disease
  • Phase II Adult respiratory distress syndrome
  • Preclinical Idiopathic pulmonary fibrosis
  • Discontinued Rheumatoid arthritis; Systemic scleroderma

Most Recent Events

  • 28 Oct 2025 Updated adverse event and efficacy data from a phase II/III trial in SARS-COV-2 acute respiratory disease released by Edesa Biotech
  • 17 Apr 2025 PPD Development initiates enrolment in a phase II trial for Respiratory distress syndrome in USA (IV) (NCT06701669)
  • 27 Nov 2024 PPD DEVELOPMENT plans phase-II trial for Adult respiratory distress syndrome in January 2025 (IV) (NCT06701669)

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