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Oremepermin alfa - Kringle Pharma

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Drug Profile

Oremepermin alfa - Kringle Pharma

Alternative Names: Hepatocyte growth factor - Kringle Pharma; KP-100 - Kringle Pharma; KP-100IT; KP-100LI

Latest Information Update: 04 Jul 2024

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At a glance

  • Originator Kringle Pharma
  • Class Antifibrotics; Growth factors; Neuropsychotherapeutics
  • Mechanism of Action Angiogenesis inducing agents; Apoptosis inhibitors; Cell death inhibitors; Proto-oncogene protein c-met modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Spinal cord injuries
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Scars; Spinal cord injuries
  • Phase II Amyotrophic lateral sclerosis
  • Phase I Acute kidney injury

Most Recent Events

  • 04 Jul 2024 Oremepermin alfa is still in phase I trial for Acute kidney injury in USA (Kringle Pharma pipeline, July 2024)
  • 24 Nov 2022 Phase-III clinical trials in Scars in Japan (Submucosal)
  • 18 Nov 2022 Kringle Pharma plans a phase III trial for Scar in Japan (Injection) (NCT05627648)

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