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Dusquetide - Soligenix

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Drug Profile

Dusquetide - Soligenix

Alternative Names: Dusquetide; IDR-1; Innate defense regulator-1; SGX-94; SGX-942; SGX-943; SGX-945

Latest Information Update: 13 Apr 2026

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At a glance

  • Originator University of British Columbia
  • Developer Soligenix; The Childrens Hospital of Philadelphia
  • Class Anti-infectives; Anti-inflammatories; Antibacterials; Antineoplastics; Peptides; Proteins
  • Mechanism of Action SQSTM1 protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Lymphoproliferative disorders; Behcet's syndrome; Acute radiation syndrome
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Stomatitis
  • Phase II Behcet's syndrome
  • Preclinical Breast cancer; Infections
  • Discontinued Bacterial infections; Lymphoproliferative disorders; Melioidosis

Most Recent Events

  • 26 Mar 2026 Dusquetide - Soligenix receives Orphan Drug status for Behcet's syndrome in European Union
  • 10 Mar 2026 Dusquetide receives Promising Innovative Medicine (PIM) designation by Medicines and Healthcare Products Regulatory Agency for Behcet's syndrome
  • 10 Mar 2026 Efficacy and adverse events data from phase IIa clinical trials in Behcet's syndrome released by Soligenix

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