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LC28 0126

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Drug Profile

LC28 0126

Alternative Names: LC-280126; NecroX-7

Latest Information Update: 28 Oct 2020

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At a glance

  • Originator LG Life Sciences
  • Developer LG Chem; LG Life Sciences
  • Class Antifibrotics; Cardiovascular therapies; Hepatoprotectants; Indoles; Small molecules; Thiazoles
  • Mechanism of Action NF-kappa B inhibitors; NFATC transcription factor inhibitors; Proto oncogene proteins c fos inhibitors; Reactive oxygen species inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Hepatic fibrosis

Highest Development Phases

  • Phase II Myocardial infarction
  • No development reported Hepatic fibrosis; Pulmonary fibrosis

Most Recent Events

  • 28 Oct 2020 No recent reports of development identified for preclinical development in Pulmonary-fibrosis in South Korea
  • 15 Nov 2017 LG Life Sciences completes a phase I trial in Healthy volunteers in South Korea (NCT03196804)
  • 07 Jun 2017 LG Life Sciences initiates enrolment in a phase I trial in Healthy volunteers in South Korea (NCT03196804)

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