LC28 0126

Drug Profile

LC28 0126

Alternative Names: LC-280126; NecroX-7

Latest Information Update: 16 Apr 2018

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At a glance

  • Originator LG Life Sciences
  • Developer LG Chem; LG Life Sciences
  • Class Antifibrotics; Cardiovascular therapies; Hepatoprotectants; Indoles; Small molecules; Thiazoles
  • Mechanism of Action NF-kappa B inhibitors; NFATC-transcription-factor-inhibitors; Proto oncogene proteins c fos inhibitors; Reactive oxygen species inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Hepatic fibrosis

Highest Development Phases

  • Phase II Myocardial infarction
  • Preclinical Pulmonary fibrosis
  • No development reported Hepatic fibrosis

Most Recent Events

  • 15 Nov 2017 LG Life Sciences completes a phase I trial in Healthy volunteers in South Korea (NCT03196804)
  • 07 Jun 2017 LG Life Sciences initiates enrolment in a phase I trial in Healthy volunteers in South Korea (NCT03196804)
  • 03 Sep 2016 Preclinical trials in Pulmonary fibrosis in South Korea (unspecified route)
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