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Calmangafodipir - Egetis Therapeutics

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Drug Profile

Calmangafodipir - Egetis Therapeutics

Alternative Names: Aladote; PledOx; PP-095; PP-100; PP-100-01; SP-04 - Solasia Pharma

Latest Information Update: 28 Nov 2024

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At a glance

  • Originator PledPharma
  • Developer Egetis Therapeutics; Solasia Pharma; University of Milan Bicocca
  • Class Acetates; Chemoprotectants; Ethylenediamines; Hepatoprotectants; Neuroprotectants; Pyridines; Small molecules
  • Mechanism of Action Antioxidants; Iron chelating agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Liver failure
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Chemotherapy-induced damage
  • Suspended Liver failure

Most Recent Events

  • 28 Nov 2024 No recent reports of development identified for preclinical development in Chemotherapy-induced-damage in China (IV, Infusion)
  • 17 Jul 2023 Preclinical trials in Chemotherapy-induced damage in Japan (IV) before July 2023 (Solasia Pharma pipeline, July 2023)
  • 05 Jul 2023 Egetis Therapeutics intends to submit NDA/MAA for Chemotherapy induced damage (Paracetamol poisoning) in 2025 (Egetis Therapeutics pipeline, July 2023)

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