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Imaprelimab - Prothena Corporation

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Drug Profile

Imaprelimab - Prothena Corporation

Alternative Names: Anti-CD146-monoclonal-antibody; Anti-MCAM-monoclonal-antibody; PRX-003

Latest Information Update: 24 Oct 2021

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At a glance

  • Originator Neotope Biosciences; Onclave Therapeutics
  • Developer Prothena
  • Class Anti-inflammatories; Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Cell adhesion molecule inhibitors; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Cancer; Inflammation; Psoriasis

Most Recent Events

  • 28 Feb 2018 Prothena Biosciences completes a phase I trial in Psoriasis in USA (IV, Infusion) (NCT02630901)
  • 29 Sep 2017 Discontinued - Phase-I for Psoriasis in USA (IV)
  • 29 Sep 2017 Discontinued - Preclinical for Inflammation in Ireland (Parenteral)

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