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Iberdomide - Bristol Myers Squibb

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Drug Profile

Iberdomide - Bristol Myers Squibb

Alternative Names: BMS 986382; CC-220; IBER

Latest Information Update: 26 Sep 2025

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At a glance

  • Originator Celgene Corporation
  • Developer Bristol-Myers Squibb; Celgene Corporation; Emory University
  • Class Anti-inflammatories; Antineoplastics; Isoindoles; Piperidones; Skin disorder therapies; Small molecules
  • Mechanism of Action Ubiquitin protein ligase complex modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Multiple myeloma
  • Phase II Smoldering multiple myeloma
  • Phase I B-cell lymphoma; Lymphoma
  • Discontinued Atopic dermatitis; Cutaneous lupus erythematosus; Follicular lymphoma; Sarcoidosis; Systemic lupus erythematosus; Systemic scleroderma

Most Recent Events

  • 23 Sep 2025 Interim efficacy and adverse events data from the phase III EXCALIBER-RRMM trial in multiple myeloma released by Bristol-Myers Squibb
  • 28 Jul 2025 Celegen corporation initiates phase-I clinical trials in Multiple myeloma (Combination therapy, Second-line therapy or greater) in USA (PO) (NCT06348108)
  • 12 Jun 2025 Updated efficacy and adverse events data from the phase Ib/IIa CC-220-MM-001 trial in Multiple myeloma released by Bristol-Myers Squibb

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