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Perhexiline - Heart Metabolics

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Drug Profile

Perhexiline - Heart Metabolics

Alternative Names: Perhexiline maleate - Heart Metabolics

Latest Information Update: 17 Sep 2021

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At a glance

  • Originator HMBL Limited
  • Developer Heart Metabolics Limited
  • Class Antihypertensives; Cyclohexanes; Ischaemic heart disorder therapies; Piperidines; Small molecules
  • Mechanism of Action Calcium channel antagonists; Carnitine O-palmitoyltransferase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cardiomyopathies
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Hypertrophic cardiomyopathy

Most Recent Events

  • 28 Jul 2018 No recent reports of development identified for phase-I development in Hypertrophic-cardiomyopathy(In volunteers) in Australia (PO, Tablet)
  • 26 Aug 2017 Efficacy and pharmacodynamics data from a phase I trial in healthy volunteers presented at the Annual Congress of the European Society of Cardiology (ESC-Card-2017)
  • 02 Aug 2017 Heart Metabolics Limited terminates a phase II trial due to lack of efficacy in Hypertrophic cardiomyopathy in USA (PO) (NCT02862600)
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