Radgocitabine - Delta-Fly Pharma
Alternative Names: CNDAC; DFP-10917; NS 917; TAS-109Latest Information Update: 12 Sep 2024
At a glance
- Originator Delta-Fly Pharma
- Developer Delta-Fly Pharma; Nippon Shinyaku
- Class Amines; Antineoplastics; Nitriles; Pyrimidines; Small molecules
- Mechanism of Action DNA-directed DNA polymerase inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III Acute myeloid leukaemia
- No development reported Precursor cell lymphoblastic leukaemia-lymphoma
Most Recent Events
- 10 Sep 2024 Phase-I/II clinical trials in Acute myeloid leukaemia (Second-line therapy or greater, Combination therapy) in USA (IV) (NCT06382168)
- 08 Apr 2024 The US FDA approves the protocol for phase I/II trial of DFP-10917 combined with Ventoclax in Acute myeloid leukemia
- 08 Mar 2024 Delta Fly Pharma had submitted the protocol to FDA of the phase I/II study of DFP 10917 combined with Venetoclax (VTX) in acute myeloid leukemia