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Radgocitabine - Delta-Fly Pharma

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Drug Profile

Radgocitabine - Delta-Fly Pharma

Alternative Names: CNDAC; DFP-10917; NS 917; TAS-109

Latest Information Update: 12 Sep 2024

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At a glance

  • Originator Delta-Fly Pharma
  • Developer Delta-Fly Pharma; Nippon Shinyaku
  • Class Amines; Antineoplastics; Nitriles; Pyrimidines; Small molecules
  • Mechanism of Action DNA-directed DNA polymerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Acute myeloid leukaemia
  • No development reported Precursor cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 10 Sep 2024 Phase-I/II clinical trials in Acute myeloid leukaemia (Second-line therapy or greater, Combination therapy) in USA (IV) (NCT06382168)
  • 08 Apr 2024 The US FDA approves the protocol for phase I/II trial of DFP-10917 combined with Ventoclax in Acute myeloid leukemia
  • 08 Mar 2024 Delta Fly Pharma had submitted the protocol to FDA of the phase I/II study of DFP 10917 combined with Venetoclax (VTX) in acute myeloid leukemia

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