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Upadacitinib - AbbVie

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Drug Profile

Upadacitinib - AbbVie

Alternative Names: ABT-494; RINVOQ; RINVOQ LQ; Upadacitinib extended release - Abbvie; Upadacitinib modified release - Abbvie; Upadacitinib prolonged release - Abbvie; Upadacitinib tartrate; Upadicitinib hemihydrate - Abbvie

Latest Information Update: 26 Aug 2026

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At a glance

  • Originator Abbott Laboratories
  • Developer AbbVie
  • Class Amides; Anti-inflammatories; Antipsoriatics; Antirheumatics; Fluorocarbons; Imidazoles; Pyrazines; Pyrroles; Pyrrolidines; Skin disorder therapies; Small molecules; Vascular disorder therapies
  • Mechanism of Action Janus kinase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Alopecia areata; Ankylosing spondylitis; Atopic dermatitis; Crohn's disease; Giant cell arteritis; Juvenile rheumatoid arthritis; Non-radiographic axial spondyloarthritis; Psoriatic arthritis; Rheumatoid arthritis; Ulcerative colitis; Vitiligo
  • Phase III Hidradenitis suppurativa; Systemic lupus erythematosus; Vasculitis

Most Recent Events

  • 20 Aug 2026 Phase-III clinical trials in Alopecia areata (In children, In adolescents) in USA (PO) (NCT07772492)
  • 14 Aug 2026 Launched for Alopecia areata (In adolescents, In adults) in USA (PO)
  • 14 Aug 2026 Launched for Vitiligo (In adults, In adolescents) in USA (PO)

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