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Research programme: acetyl CoA carboxylase 1/2 allosteric inhibitors - Gilead Sciences

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Drug Profile

Research programme: acetyl CoA carboxylase 1/2 allosteric inhibitors - Gilead Sciences

Alternative Names: ND-630; ND-646; ND-654

Latest Information Update: 28 May 2022

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At a glance

  • Originator Nimbus Discovery
  • Developer Gilead Sciences; Nimbus Therapeutics
  • Class Small molecules
  • Mechanism of Action Acetyl-CoA carboxylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • No development reported Breast cancer; Diabetes mellitus; Liver cancer; Metabolic syndrome; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Non-small cell lung cancer

Most Recent Events

  • 28 May 2022 No recent reports of development identified for preclinical development in Non-alcoholic-fatty-liver-disease in USA
  • 28 May 2020 No recent reports of development identified for preclinical development in Breast-cancer in USA (PO)
  • 28 May 2018 No recent reports of development identified for preclinical development in Non-small-cell-lung-cancer in USA

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