MIN 117

Drug Profile

MIN 117

Alternative Names: MIN-117; Wf-516; WF516

Latest Information Update: 28 May 2018

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At a glance

  • Originator Mitsubishi Tanabe Pharma Corporation
  • Developer Minerva Neurosciences
  • Class Antidepressants; Oxadiazoles; Piperidines; Small molecules
  • Mechanism of Action Alpha 1 adrenergic receptor modulators; Serotonin 1A receptor antagonists; Serotonin 2A receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Major depressive disorder

Most Recent Events

  • 09 Apr 2018 Phase-II clinical trials in Major depressive disorder in USA (PO) (NCT03446846)
  • 12 Mar 2018 Minerva neurosciences completes a phase I food effect trial
  • 06 Nov 2017 Minerva Neurosciences plans to initiate a phase IIb trial of MIN 117 for Major depressive disorder (including mood and anxiety disorders) in USA by early 2018 (PO) (NCT03446846)
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