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PHP 303

Drug Profile

PHP 303

Alternative Names: BAY 858501; PHP-303

Latest Information Update: 14 Mar 2021

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At a glance

  • Originator Bayer HealthCare
  • Developer Bayer HealthCare; pH Pharma
  • Class Antibronchitics; Benzenesulfonates; Fluorinated hydrocarbons; Hepatoprotectants; Nitriles; Pyrimidines; Small molecules
  • Mechanism of Action Leucocyte elastase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Alpha 1-antitrypsin deficiency
  • Phase I Non-alcoholic steatohepatitis
  • No development reported Bronchiectasis

Most Recent Events

  • 04 May 2020 Phase-II clinical trials in Alpha 1-antitrypsin deficiency in United Kingdom (PO) (EudraCT2019-002501-22)
  • 07 Apr 2020 pH Pharma completes a phase I clinical trials in Non-alcoholic steatohepatitis (In volunteers) in USA (NCT03775278)
  • 19 Dec 2018 No development reported - Phase-II for Bronchiectasis (Non-cystic fibrosis related) in Italy, Germany, France, Spain, United Kingdom (PO)
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