Research programme: cancer therapeutics - Regen BioPharma

Drug Profile

Research programme: cancer therapeutics - Regen BioPharma

Alternative Names: Checkpoint inhibitor pill - Regen BioPharma; dCellVax™; DiffronC; IDO-silenced cancer immunotherapeutic - Regen Biopharma; IDO-silenced dendritic cell vaccine - Regen Biopharma; NR2F6 inhibitors - Regen BioPharma; NR2F6 T cell immunotherapy; NR2F6-silenced cancer therapeutics - Regen BioPharma; RGBP-248; tCellVax; ucVAX; Universal donor cell therapy - Regen BioPharma

Latest Information Update: 28 Jul 2018

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At a glance

  • Originator University of Western Ontario
  • Developer Regen BioPharma; University of Lausanne; University of Western Ontario
  • Class Cancer vaccines; Dendritic cell vaccines; Gene therapies; Small interfering RNA; Small molecules
  • Mechanism of Action Dendritic cell modulators; Gene silencing; Gene transference; Immunostimulants; RNA interference; Stem cell modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Cancer; Liver cancer
  • Research Breast cancer; Colorectal cancer; Leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 28 Jul 2018 No recent reports of development identified for preclinical development in Breast-cancer in Canada (IV, Injection)
  • 15 Dec 2016 Regen BioPharma files a utility patent application with the USPTO for NR2F6 silenced CAR-T cells in USA
  • 14 Sep 2016 Regen BioPharma resubmits IND application with the US FDA for Breast cancer (Metastatic disease)
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