Esketamine - Johnson & Johnson

Drug Profile

Esketamine - Johnson & Johnson

Alternative Names: JNJ-54135419; S-ketamine

Latest Information Update: 16 Apr 2018

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At a glance

  • Originator Johnson & Johnson
  • Class Analgesics; Antidepressants; Chlorobenzenes; Cyclohexanones; General anaesthetics; Small molecules
  • Mechanism of Action NMDA receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase III Major depressive disorder

Most Recent Events

  • 09 Apr 2018 Janssen suspends a phase II trial in Major depressive disorder (Adjunctive treatment, In adolescents, In children) in Spain, Hungary, Poland, France, Bulgaria, Brazil, Belgium, USA, Italy for new subject recruitment due interruption in clinical supplies(Intranasal) (NCT03185819)
  • 15 Feb 2018 Janssen Research & Development plans a phase III trial for Major depressive disorder (Treatment-resistant) (Combination therapy) in China (NCT03434041)
  • 02 Feb 2018 Janssen Research and Development completes a phase-I trial for Renal failure in USA (Intranasal) (NCT02606084)
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