Esketamine - Johnson & Johnson

Drug Profile

Esketamine - Johnson & Johnson

Alternative Names: Esketamine nasal spray; JNJ-54135419; S-ketamine

Latest Information Update: 13 Jul 2018

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At a glance

  • Originator Johnson & Johnson
  • Class Analgesics; Antidepressants; Chlorobenzenes; Cyclohexanones; General anaesthetics; Small molecules
  • Mechanism of Action NMDA receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase III Major depressive disorder

Most Recent Events

  • 22 Jun 2018 Updated efficacy data from the phase III SUSTAIN-1 and SUSTAIN-2 trials in Major depressive disorder released by Janssen Research & Development
  • 31 May 2018 Efficacy and adverse events data from the phase III SUSTAIN-1 and SUSTAIN-2 trials in Major depressive disorder released by Johnson & Johnson
  • 25 May 2018 Phase-III clinical trials in Major depressive disorder (Combination therapy, Treatment-resistant) in China (Intranasal) (NCT03434041)
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