P 1037

Drug Profile

P 1037

Alternative Names: GS-5737; P-1037; VX 371

Latest Information Update: 02 Nov 2017

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At a glance

  • Originator Parion Sciences
  • Developer Parion Sciences; Vertex Pharmaceuticals
  • Class Antibronchitics
  • Mechanism of Action Epithelial sodium channel-antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cystic fibrosis; Primary ciliary dyskinesia

Most Recent Events

  • 25 Oct 2017 Safety and efficacy data from a phase IIa trial in Cystic fibrosis released by Vertex Pharmaceuticals
  • 01 Sep 2017 Vertex Pharmaceuticals completes a phase II trial in Cystic fibrosis (In adolescents, In adults) in USA, United Kingdom, Czech Republic, France and Ireland (Inhalation) (NCT02709109)
  • 23 Feb 2017 Vertex Pharmaceuticals has patent protection for P 1037 in USA and outside USA (Vertex Pharmaceuticals form 10-K, filed in February 2017)
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