GSK 3532795
Alternative Names: BMS 955176; GSK-3532795; HIV maturation inhibitor - GSK/ViiV HealthcareLatest Information Update: 05 Nov 2023
At a glance
- Originator Bristol-Myers Squibb
- Developer GlaxoSmithKline; Senopsys; ViiV Healthcare
- Class Amines; Antivirals; Benzoic acids; Chrysenes; Cyclopentanes; Small molecules; Thiazines
- Mechanism of Action HIV replication inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued HIV-1 infections
Most Recent Events
- 25 Sep 2017 Bristol-Myers Squibb terminates a phase II trial due to GI intolerability in HIV-1 infections (Combination therapy, Treatment-experienced) in USA, Puerto Rico, Australia, Chile, Mexico, Taiwan, Argentina, Canada, Colombia, Peru, Russia, South Africa, and Thailand (PO) (NCT02386098)
- 21 Aug 2017 Bristol-Myers Squibb terminates phase II trial in HIV-1 infections (Combination therapy, Treatment-naive) in USA, Argentina, Canada, Chile, Mexico, Puerto Rico, Poland, United Kingdom, France, Germany, Spain, Italy, South Africa and Thailand (NCT02415595)
- 01 Mar 2017 ViiV Healthcare withdraws a phase I trial in volunteers in USA prior to enrolment, due to neuropsychiatric serious adverse events reported by two participants (NCT02576119)