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Alternative Names:
[11C]AZD9291; [11C]osimertinib; ADAURA; AZD-9291; Mereletinib; TAGRISSO; Tagrisso
Latest Information Update: 15 Sep 2021
Price :
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At a glance
Originator
AstraZeneca
Developer
AstraZeneca; Dana-Farber Cancer Institute; Eli Lilly and Company; European Organisation for Research and Treatment of Cancer; European Thoracic Oncology Platform; G1 Therapeutics; Genprex; HUTCHMED; Incyte Corporation; Kyushu University; Molecular Partners AG; National Cancer Institute (USA); National University Hospital (Singapore); Princess Margaret Hospital (University of Toronto); Singapore Clinical Research Institute; Sunnybrook Health Sciences Centre; University of California at San Francisco
Class
Acrylamides; Aniline compounds; Antineoplastics; Dimethylamines; Indoles; Pyrimidines; Small molecules
Mechanism of Action
Epidermal growth factor receptor antagonists
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
Yes
-
Non-small cell lung cancer
New Molecular Entity
Yes
Highest Development Phases
Marketed
Non-small cell lung cancer
Phase II
Adenocarcinoma; Glioblastoma; Meningeal carcinomatosis
No development reported
Solid tumours
Most Recent Events
09 Sep 2021
Phase-III clinical trials in Non-small cell lung cancer (Combination therapy, Late-stage disease, Metastatic disease, In adults, First-line therapy) in China (PO)
08 Sep 2021
AstraZeneca completes a phase I/II trial in Non-small cell lung cancer (Late-stage disease, Combination therapy, Second-line therapy or greater) in Japan (jRCTs051180183)
20 Aug 2021
HUTCHMED plans the phase III SACHI trial for Non-small cell lung cancer (Combination therapy, Second-line therapy or greater) in China in August 2021 (NCT05015608)
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