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Tumour cells apoptosis factor - Immune System Key

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Drug Profile

Tumour cells apoptosis factor - Immune System Key

Alternative Names: 84AA–API 14AA; Nerofe

Latest Information Update: 28 Jul 2023

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At a glance

  • Originator Immune System Key
  • Developer Immune System Key; University of Miami
  • Class Antineoplastics; Cardiovascular therapies; Peptide hormones
  • Mechanism of Action Angiogenesis inhibitors; Apoptosis stimulants; Interleukin 1 receptor-like 1 protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acute myeloid leukaemia; Myelodysplastic syndromes
  • Phase I/II Ovarian cancer; Triple negative breast cancer
  • Phase I Solid tumours
  • Discontinued Myocardial infarction

Most Recent Events

  • 28 Jul 2023 No recent reports of development identified for phase-I development in Acute-myeloid-leukaemia(Monotherapy) in USA (IV, Infusion)
  • 28 Jul 2023 No recent reports of development identified for phase-I development in Myelodysplastic-syndromes(Late-stage disease, Monotherapy, Second-line therapy or greater) in USA (IV, Infusion)
  • 01 Feb 2023 Phase-I clinical trials in Solid tumours (Late-stage disease, Inoperable/Unresectable, Combination therapy, Second-line therapy or greater, Metastatic disease) in USA (IV) (NCT05661201)

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