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Etrasimod - Pfizer

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Drug Profile

Etrasimod - Pfizer

Alternative Names: APD-334; Etrasimod arginine - Pfizer; Etrasimod L-arginine; PF-07915503; VELSIPITY; Verespiti

Latest Information Update: 23 Mar 2026

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At a glance

  • Originator Arena Pharmaceuticals
  • Developer Arena Pharmaceuticals; Everest Medicines; Pfizer
  • Class 3-ring heterocyclic compounds; Acetic acids; Amino acids; Anti-inflammatories; Benzene derivatives; Cyclopentanes; Ethers; Fluorinated hydrocarbons; Indoles; Skin disorder therapies; Small molecules
  • Mechanism of Action Sphingosine 1 phosphate receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Eosinophilic oesophagitis
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Ulcerative colitis
  • Phase II/III Atopic dermatitis
  • Phase II Eosinophilic oesophagitis
  • Discontinued Alopecia areata; Crohn's disease; Inflammatory bowel diseases; Primary biliary cirrhosis; Pyoderma gangrenosum

Most Recent Events

  • 11 Mar 2026 Launched for Ulcerative colitis in China (PO)
  • 11 Mar 2026 Efficacy and adverse event data from a phase III ELEVATE UC OLE trial in Ulcerative colitis released by Everest Medicines
  • 11 Mar 2026 Efficacy data from a phase III ENLIGHT UC trial in Ulcerative colitis released by Everest Medicines

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