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Insulin icodec - Novo Nordisk

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Drug Profile

Insulin icodec - Novo Nordisk

Alternative Names: 148-0287-A; AWIQLI; Insulin 287; LAI-287; Long-acting basal insulin analogue-287 - Novo-Nordisk; Long-acting-insulin-287 - Novo-Nordisk; NN-1436; NN-1956; NNC-0148-0000-0287; NNC0148-0287 C; OI 287GT

Latest Information Update: 29 Jul 2025

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At a glance

  • Originator Novo Nordisk
  • Class Antihyperglycaemics; Insulins; Pancreatic hormones
  • Mechanism of Action Insulin receptor agonists; Ornithine decarboxylase stimulants; Phosphokinase stimulants; Protein tyrosine kinase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Type 1 diabetes mellitus; Type 2 diabetes mellitus

Most Recent Events

  • 14 Jul 2025 Novo Nordisk plans a phase III ONWARDS 11 trial for Type 1 diabetes mellitus(Combination therapy) in Australia, Canada, Germany, Poland, Puerto Rico, Romania, Slovakia, USA (SC, Injection) in August 2025 (NCT07076199)(EudraCT2024-519945-31)
  • 13 Jun 2025 Novo Nordisk completes a phase III trial in Type 2 diabetes mellitus (Treatment-experienced) in the US, Bulgaria, Germany, Japan, Poland, Puerto Rico, Spain, India, South Africa (SC) (NCT06340854)
  • 16 May 2025 Novo Nordisk completes a phase III trial in Type 2 diabetes mellitus (Combination therapy) in Czech Republic, Malaysia, Poland, Serbia, and Thailand (SC) (NCT05813912)

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