AZD 2811

Drug Profile

AZD 2811

Alternative Names: AZD 1152 hQPA; AZD2811

Latest Information Update: 28 Jul 2018

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At a glance

  • Originator AstraZeneca; BIND Therapeutics
  • Developer AstraZeneca; Pfizer
  • Class Acetamides; Antineoplastics; Fluorobenzenes; Pyrazoles; Quinazolines
  • Mechanism of Action Aurora kinase B inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Small cell lung cancer
  • Phase I/II Acute myeloid leukaemia; Myelodysplastic syndromes
  • Phase I Solid tumours
  • No development reported Diffuse large B cell lymphoma

Most Recent Events

  • 28 Jul 2018 No recent reports of development identified for preclinical development in Diffuse large B cell lymphoma in USA (Controlled release)
  • 29 Jun 2018 Preliminary efficacy, pharmacokinetics and adverse events data from a phase I trial in Solid tumors presented at the 54th Annual Meeting of the American Society of Clinical Oncology
  • 14 Dec 2017 Samsung Medical Center plans the phase II SUKSES-N3 trial for Small cell lung cancer (Second-line therapy or greater) (IV) in December 2017 (NCT03366675)
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