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LB 100

Drug Profile

LB 100

Alternative Names: LB-1; LB-100

Latest Information Update: 23 Jun 2022

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At a glance

  • Originator Lixte Biotechnology Holdings
  • Developer City of Hope National Medical Center; INSERM; Lixte Biotechnology Holdings; National Cancer Institute (USA)
  • Class Anti-ischaemics; Antidepressants; Antineoplastics; Behavioural disorder therapies; Carboxylic acids; Heterocyclic bicyclo compounds; Piperazines; Small molecules
  • Mechanism of Action Protein phosphatase 2A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Breast cancer

Highest Development Phases

  • Phase II Glioblastoma
  • Phase I/II Myelodysplastic syndromes
  • Phase I Small cell lung cancer
  • Preclinical Angelman syndrome; Behavioural disorders
  • No development reported Ischaemia; Solid tumours
  • Discontinued Depressive disorders; Haematological disorders

Most Recent Events

  • 12 Apr 2022 Pharmacodynamics data from a preclinical trial in cancer presented at the Annual Meeting of American Association for Cancer Research (AACR-2022)
  • 23 Mar 2022 Lixte Biotechnology has patents pending for LB 100 in the US
  • 23 Mar 2022 Lixte Biotechnology has patent protection for LB 100, in multiple countries
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