Drug Profile


Alternative Names: Dexketoprofen trometamol/tramadol; Dexketoprofen trometamol/tramadol hydrochloride; Dexketoprofen/tramadol hydrochloride; Dexketoprofene/tramadolo; DKP.TRIS/TRAM; DKP.TRIS/TRAM.HCL; DKP/TRAM; DKP/TRAM.HCL; Lenizak; Skudex; Skudexa; Skudexum; Skudo; TRAM.HCL/DKP; TRAM.HCL/DKP.TRIS; TRAM/DKP; TRAM/DKP.TRIS; Tramadol hydrochloride/dexketoprofen; Tramadol hydrochloride/dexketoprofen trometamol; Tramadol/dexketoprofen; Tramadol/dexketoprofen trometamol

Latest Information Update: 24 Nov 2016

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At a glance

  • Originator Menarini Ricerche
  • Class Cyclohexanols; Dimethylamines; Nonsteroidal anti-inflammatories; Opioid analgesics; Phenylpropionates; Propylene glycols; Small molecules
  • Mechanism of Action Adrenergic uptake inhibitors; Cyclooxygenase inhibitors; Opioid mu receptor agonists; Serotonin uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Acute pain

Most Recent Events

  • 26 Sep 2016 Interim efficacy data from two pivotal phase III trials in Post-operative pain presented at the 16th World Congress on pain (WCP-2016)
  • 17 Aug 2016 Launched for Acute pain (In adults) in United Kingdom (PO) before August 2016
  • 17 Aug 2016 Preregistration for Acute pain in Russia, Ukraine, Taiwan and Serbia (PO) before August 2016 (Menarini website)
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