Andecaliximab - Gilead Sciences

Drug Profile

Andecaliximab - Gilead Sciences

Alternative Names: Anti-matrix metalloproteinase-9 monoclonal antibody; Anti-MMP9 monoclonal antibody; GS-5745; MMP9 mAb inhibitor

Latest Information Update: 12 Jun 2018

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At a glance

  • Originator Gilead Sciences
  • Class Antineoplastics; Antiulcers; Monoclonal antibodies
  • Mechanism of Action Matrix metalloproteinase 9 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Gastric cancer
  • Phase I Solid tumours
  • Discontinued Chronic obstructive pulmonary disease; Crohn's disease; Cystic fibrosis; Rheumatoid arthritis; Ulcerative colitis

Most Recent Events

  • 01 Jun 2018 Efficacy and adverse events data from a phase Ib trial in Solid tumours presented at the 54th Annual Meeting of the American Society of Clinical Oncology (ASCO-2018)
  • 27 Feb 2018 Gilead Sciences has patent protection for andecaliximab in USA
  • 27 Feb 2018 Gilead has patents pending for andecaliximab in European Union
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