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LHW 090

Drug Profile

LHW 090

Alternative Names: LHV-527; LHW090

Latest Information Update: 19 Mar 2019

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At a glance

  • Originator Novartis
  • Class Antihypertensives
  • Mechanism of Action Neprilysin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Kidney disorders
  • Discontinued Resistant hypertension

Most Recent Events

  • 19 Mar 2019 Discontinued - Phase-II for Resistant hypertension in USA, France, Denmark, Germany, Netherlands, Switzerland (PO)
  • 10 Nov 2018 Efficacy, adverse events and pharmacodynamics data from a phase II trial in Resistant hypertension presented at the 91st Annual Scientific Sessions of the American Heart Association (AHA-2018)
  • 11 Oct 2018 Novartis completes a phase II trial in Kidney disorders in USA and Germany (NCT02678000) (EudraCT2015-004570-15)
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