Drug Profile

Apimostinel - AbbVie

Alternative Names: AGN 241660; GATE-202; NRX-1074

Latest Information Update: 28 Dec 2024

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At a glance

Originator Naurex
Developer AbbVie; Gate Neurosciences; Naurex
Class Amides; Antidepressants; Small molecules
Mechanism of Action NMDA receptor agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Major depressive disorder

Most Recent Events

28 Dec 2024 No recent reports of development identified for phase-I development in Major depressive disorder(In volunteers) in USA (PO)
24 Oct 2024 Phase-II clinical trials in Major depressive disorder (Treatment-experienced) in USA (IV) (NCT06400121)
16 May 2024 Pharmacodynamics data from preclinical studies released by Gate Neurosciences

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