ARX 788

Drug Profile

ARX 788

Alternative Names: Antibody-drug conjugate - Ambrx/Zhejiang Medicine; ARX788

Latest Information Update: 21 Mar 2018

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At a glance

  • Originator Ambrx
  • Developer Ambrx; Zhejiang Medicine
  • Class Antineoplastics; Drug conjugates; Immunotoxins; Monoclonal antibodies; Small molecules
  • Mechanism of Action Tubulin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Cancer
  • Preclinical Gastric cancer

Most Recent Events

  • 12 Mar 2018 Phase-I clinical trials in Cancer (Late-stage disease, In adults, In the elderly, Second-line therapy or greater) in Australia, USA (IV) (NCT03255070)
  • 23 Aug 2017 Ambrx plans a phase I trial for Cancer (Late-stage disease, Second-line therapy or greater) (NCT03255070)
  • 19 Aug 2016 The US FDA approves IND application for a phase I trial of ARX 788
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