Drug Profile


Alternative Names: MHAA-4549A; RG 7745; RO 6876802

Latest Information Update: 08 May 2018

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At a glance

  • Originator Genentech
  • Class Antivirals; Monoclonal antibodies
  • Mechanism of Action Influenza virus haemagglutinin glycoprotein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Influenza A virus infections

Most Recent Events

  • 21 Apr 2018 Efficacy and adverse events data from a phase IIb trial in Influenza-A virus infections presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID-2018)
  • 13 Nov 2017 Genentech completes a phase II trial in Influenza-A virus infections (Monotherapy) in USA, Canada, South Korea, New Zealand, South Africa, Spain, and United Kingdom (IV) (NCT02623322)
  • 23 May 2017 Genentech completes a phase II trial in Influenza-A virus infections (Combination therapy) in Belgium, Brazil, Bulgaria, Canada, Chile, Czech Republic, France, Germany, Hong Kong, Hungary, Italy, Netherlands, New Zealand, Peru, Poland, South Korea, Spain, Sweden and United Kingdom, Taiwan, Ukraine, Russia, South Africa, Mexico, Israel (NCT02293863)
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