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Pavinetant - Tempest Therapeutics

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Drug Profile

Pavinetant - Tempest Therapeutics

Alternative Names: AZ 12472520; AZD 2624; AZD 4901; MLE-4901

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator AstraZeneca
  • Developer AstraZeneca; Tempest Therapeutics
  • Class Small molecules
  • Mechanism of Action Hormone modulators; Neurokinin 3 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Hot flashes; Polycystic ovary syndrome; Schizophrenia

Most Recent Events

  • 08 Nov 2017 Discontinued - Phase-II for Hot flashes in United Kingdom (PO)
  • 08 Nov 2017 Discontinued - Phase-II for Polycystic ovary syndrome in USA, Germany, United Kingdom (PO)
  • 08 Nov 2017 Millendo Therapeutics terminates a phase II trial in Hot flashes in United Kingdom after assessment of the clinical risks and benefits of the program (PO) (NCT02668185)

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