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AZD 8186

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Drug Profile

AZD 8186

Alternative Names: AZD-8186

Latest Information Update: 30 Oct 2021

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At a glance

  • Originator AstraZeneca
  • Developer AstraZeneca; National Cancer Institute (USA)
  • Class Amides; Amines; Antineoplastics; Fluorobenzenes; Morpholines; Pyrones; Small molecules
  • Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Non-small cell lung cancer; Prostate cancer; Solid tumours; Triple negative breast cancer

Most Recent Events

  • 26 Apr 2019 Discontinued - Phase-I for Non-small cell lung cancer (Late-stage disease, Second-line therapy or greater) in Spain, United Kingdom, USA and Canada (PO) (AstraZeneca pipeline, April 2019)
  • 26 Apr 2019 Discontinued - Phase-I for Prostate cancer (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in USA (PO) (AstraZeneca pipeline, April 2019)
  • 26 Apr 2019 Discontinued - Phase-I for Prostate cancer (Late-stage disease, Second-line therapy or greater) in Spain, United Kingdom, USA and Canada (PO) (AstraZeneca pipeline, April 2019)

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