sEphB4-HSA - VasGene Therapeutics

Drug Profile

sEphB4-HSA - VasGene Therapeutics

Alternative Names: EphB4-HSA; EphB4-Human Serum Albumin; Human Serum Albumin-EphB4 conjugate; Recombinant EphB4-HSA Fusion Protein; Vas 01

Latest Information Update: 03 Jul 2018

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At a glance

  • Originator VasGene Therapeutics
  • Developer National Cancer Institute (USA); University of Southern California; VasGene Therapeutics
  • Class Antineoplastics; Recombinant fusion proteins
  • Mechanism of Action EphB4 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acute myeloid leukaemia; Bladder cancer; Chronic myelomonocytic leukaemia; Head and neck cancer; Kaposi's sarcoma; Myelodysplastic syndromes; Non-small cell lung cancer; Solid tumours
  • Phase I Prostate cancer; Renal cancer

Most Recent Events

  • 18 Jun 2018 Vasgene Therapeutics plans a phase I trial for Bladder Carcinoma (Second line therapy or greater; Refractory metastatic disease) in USA (NCT03552796)
  • 01 Jun 2018 Interim adverse events data from a phase I trial Solid tumours presented at the 54th Annual Meeting of the American Society of Clinical Oncology (ASCO-2018)
  • 09 May 2018 Vasgene Therapeutics plans a phase I trial for Leukaemia in USA , (NCT03519984)
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