Rovalpituzumab tesirine - Stemcentrx

Drug Profile

Rovalpituzumab tesirine - Stemcentrx

Alternative Names: Rova-T; SC16LD6.5

Latest Information Update: 28 Mar 2018

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At a glance

  • Originator Stemcentrx
  • Developer Bristol-Myers Squibb; Stemcentrx
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DLL3 protein inhibitors; DNA modulators; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Small cell lung cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Small cell lung cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 05 Jun 2018 AbbVie plans a phase II trial for Cancer in August 2018 (NCT03543358)
  • 22 Mar 2018 Interim efficacy and adverse events data from the phase II TRINITY trial in Small cell lung cancer released by AbbVie
  • 22 Mar 2018 Stemcentrx completes enrolment in its phase II TRINITY trial for Small cell lung cancer in France, Germany, Hungary, Poland, Spain and USA (NCT02674568)
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