RBX 2660

Drug Profile

RBX 2660

Alternative Names: Microbiota restoration therapy; Microbiota suspension; RBX-2660

Latest Information Update: 03 May 2018

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At a glance

  • Originator Rebiotix
  • Developer Rebiotix; University of Alberta
  • Class Antibacterials; Antidiarrhoeals; Antiulcers; Hepatoprotectants; Immunotherapies
  • Mechanism of Action Gastrointestinal microbiome modulators; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Clostridium infections
  • New Molecular Entity No

Highest Development Phases

  • Phase III Clostridium-difficile-infections
  • Phase I/II Hepatic encephalopathy; Urinary tract infections
  • Phase I Vancomycin-resistant enterococcal infections
  • Phase 0 Inflammatory bowel diseases; Ulcerative colitis

Most Recent Events

  • 24 Apr 2018 Pooled efficacy data from the phase II PUNCH CD2 and PUNCH SOS trials in Clostridium difficile infections presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases
  • 21 Apr 2018 Pooled safety data from the phase II PUNCH CD2 and PUNCH SOS trials in Clostridium difficile infections presented 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID-2018)
  • 08 Feb 2018 Phase-I/II clinical trials in Urinary tract infections (Recurrent, Treatment-experienced) in USA (Rectal) (NCT03367910)
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