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Elexacaftor - Vertex Pharmaceuticals

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Drug Profile

Elexacaftor - Vertex Pharmaceuticals

Alternative Names: VX-445

Latest Information Update: 30 Oct 2021

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At a glance

  • Originator Cystic Fibrosis Foundation Therapeutics; Vertex Pharmaceuticals
  • Developer Vertex Pharmaceuticals
  • Class Fluorinated hydrocarbons; Pyrazoles; Pyridines; Pyrrolidines; Small molecules; Sulfonamides
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Cystic fibrosis

Most Recent Events

  • 06 Nov 2019 Discontinued - Phase-II for Cystic fibrosis in USA, Australia, Belgium, Netherlands (PO) (Vertex Pharmaceuticals pipeline, November 2019)
  • 22 Oct 2019 Chemical structure information added
  • 26 Apr 2018 Efficacy and safety data from a phase II trial in Cystic fibrosis released by Vertex Pharmaceuticals

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