Ingenol disoxate - LEO Pharma

Drug Profile

Ingenol disoxate - LEO Pharma

Alternative Names: LEO-43204

Latest Information Update: 29 Jun 2018

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At a glance

  • Originator LEO Pharma
  • Class Antiacnes; Antineoplastics; Carboxylic acids; Cyclopropanes; Esters; Isoxazoles; Small molecules
  • Mechanism of Action Apoptosis stimulants; Protein kinase C stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Actinic keratosis; Squamous cell cancer
  • Phase II Acne vulgaris

Most Recent Events

  • 15 Jun 2018 LEO Pharma terminates a phase III trial in Squamous cell carcinoma (Prevention, Second-line therapy or greater, In adolescents, In adults, In children, In the elderly) in USA, Canada, France, Germany, Spain and United Kingdom (NCT03115476)
  • 01 Nov 2017 LEO Pharma completes a phase III trial for Actinic keratosis in United Kingdom and USA (Topical) (EudraCT2015-002449-71) (NCT02547233)
  • 10 Aug 2017 LEO Pharma completes a phase III trial in Actinic keratosis in USA and Germany (NCT02549339)
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