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Bisantrene - Race Oncology

Drug Profile

Bisantrene - Race Oncology

Alternative Names: Bisantrene-hydrochloride - Race Oncology; CL-216942; Cyabin; NSC-337766; Orange Crush; RC-110; RC-220; UPI-928; XANTRENE; Zantrene

Latest Information Update: 28 Aug 2025

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At a glance

  • Originator Wyeth Pharmaceuticals
  • Developer Race Oncology; Sheba Medical Center; Wyeth Pharmaceuticals
  • Class Aldehydes; Anthracenes; Antineoplastics; Cytostatic antibiotics; Hydrazones; Imidazoles; Small molecules
  • Mechanism of Action DNA modulators; Telomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity No

Highest Development Phases

  • Phase II Acute myeloid leukaemia
  • Phase I/II Breast cancer
  • Phase I Solid tumours
  • Preclinical Lung cancer; Malignant melanoma; Renal cell carcinoma
  • Research Cancer
  • No development reported Chronic myelomonocytic leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 28 Aug 2025 No recent reports of development identified for phase-I development in Acute-myeloid-leukaemia(Combination therapy, In the elderly, Second-line therapy or greater, In adults) in Australia (IV, Infusion)
  • 28 Aug 2025 No recent reports of development identified for phase-I development in Chronic-myelomonocytic-leukaemia(Combination therapy, First-line therapy, In the elderly, In adults) in Australia (IV)
  • 28 Aug 2025 No recent reports of development identified for phase-I development in Chronic-myelomonocytic-leukaemia(Combination therapy, In the elderly, Second-line therapy or greater, In adults) in Australia (IV)

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