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Tibulizumab - Zura Bio

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Drug Profile

Tibulizumab - Zura Bio

Alternative Names: Anti-BAFF IL-17A monoclonal antibody - Eli Lilly and Company; BAFF/IL-17A-Eli-Lilly and Company; LY-3090106; ZB-106

Latest Information Update: 28 Aug 2025

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At a glance

  • Originator Eli Lilly and Company
  • Developer Eli Lilly and Company; Zura Bio
  • Class Anti-inflammatories; Antirheumatics; Bispecific antibodies; Skin disorder therapies; Small molecules
  • Mechanism of Action B cell activating factor inhibitors; Interleukin 17 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hidradenitis suppurativa; Systemic scleroderma
  • Phase I Rheumatoid arthritis; Sjogren's syndrome

Most Recent Events

  • 20 May 2025 Phase-II clinical trials in Hidradenitis suppurativa in Canada (SC) (NCT06993610)
  • 20 May 2025 Phase-II clinical trials in Hidradenitis suppurativa in USA (SC) (NCT06993610)(EudraCT2024-519736-17-00)
  • 16 May 2025 Phase-II clinical trials in Hidradenitis suppurativa in Hungary, Poland, Germany, Spain (SC) (NCT06993610)

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