RG 6149

Drug Profile

RG 6149

Alternative Names: AMG 282; MSTT 1041 A; RG6149; RO 7187807; ST2 MAb

Latest Information Update: 08 Aug 2018

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At a glance

  • Originator Amgen
  • Developer Amgen; Genentech
  • Class Antiasthmatics; Bronchodilators; Monoclonal antibodies
  • Mechanism of Action Interleukin 1 receptor-like 1 protein antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Allergic asthma; Asthma
  • Preclinical Chronic obstructive pulmonary disease
  • No development reported Rhinosinusitis

Most Recent Events

  • 31 Jul 2018 Preclinical trials in Chronic obstructive pulmonary disease in United Kingdom (SC) (NCT03615040)
  • 31 Jul 2018 Genentech plans the COPD-ST2OP phase II trial for Chronic obstructive pulmonary disease in United Kingdom (NCT03615040)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Allergic-asthma in USA (IV)
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