Nitric oxide inhalation - AIT

Drug Profile

Nitric oxide inhalation - AIT

Alternative Names: AIT-BRO; AIT-CF; AIT-COPD; AIT-NTM; AIT-NV; AIT-RSV; AIT-WH; Nitric oxide inhaled; NOxAST; NOxBR; NOxCF; NOxCureBR; NOxCureCF; NOxPN

Latest Information Update: 15 Jun 2018

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At a glance

  • Originator University of British Columbia
  • Developer AIT; Schneider Childrens Medical Center of Israel; University of British Columbia
  • Class Anti-inflammatories; Antiacnes; Antiandrogens; Antibacterials; Antifibrotics; Antifungals; Antihypertensives; Antivirals; Free radicals; Macromolecular substances; Nitrogen oxides; Non-opioid analgesics; Small molecules; Vasodilators
  • Mechanism of Action Androgen receptor antagonists; Angiogenesis inducing agents; Cell death stimulants; Guanylate cyclase stimulants; Nitric oxide donors; Reactive oxygen species modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mycobacterial infections; Cystic fibrosis
  • New Molecular Entity No

Highest Development Phases

  • Phase III Bronchitis
  • Phase II Chronic obstructive pulmonary disease; Cystic fibrosis; Diabetic foot ulcer; Mycobacterial infections; Stroke
  • No development reported Respiratory tract infections
  • Discontinued Asthma; Pneumonia

Most Recent Events

  • 13 Jun 2018 Interim adverse events and efficacy data from the phase III NO-BRO trial for Bronchitis released by AIT Therapeutics
  • 13 Jun 2018 AIT Therapeutics plans a pivotal trial for Bronchiolitis in USA (Inhalation) in the fourth quarter of 2019
  • 23 May 2018 Adverse events data from a phase II trial in Mycobacterial infections (nontuberculous) released by AIT Therapeutics
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