Icenticaftor - Novartis
Alternative Names: NVP-QBW-251; QBW-251Latest Information Update: 13 Oct 2023
At a glance
- Originator Novartis
- Class Amides; Amines; Antifibrotics; Ethers; Fluorinated hydrocarbons; Pyridines
- Mechanism of Action Cystic fibrosis transmembrane conductance regulator stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Phase II Bronchiectasis; Cystic fibrosis
- Discontinued Chronic obstructive pulmonary disease
Most Recent Events
- 13 Oct 2023 700318808- Trial termination info added to KDM and HE
- 21 Jul 2023 Novartis terminates a phase-II trial in Bronchiectasis in Germany, Spain, China, United Kingdom (PO), due to strategic business decision (NCT04396366)
- 05 Apr 2023 Discontinued - Phase-II for Chronic obstructive pulmonary disease (In the elderly, In adults) in Poland (PO) before March 2023