Pyrotinib - Jiangsu Hengrui Medicine
Alternative Names: BLTN; Irene; Pyrotinib maleate; Pyrroltinib maleate; SHR 1258Latest Information Update: 11 Apr 2025
At a glance
- Originator Shanghai Hengrui Pharmaceutical
- Developer Chinese Academy of Medical Sciences; Fudan University; Jiangsu Hengrui Medicine Co.; Peking Union Medical College Hospital; Shanghai Changzheng Hospital; Sun Yat-Sen University; Tongji University
- Class Antineoplastics; Pyridines; Pyrrolidines; Quinolines; Small molecules
- Mechanism of Action Epidermal growth factor receptor antagonists; ERBB 2 receptor antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed HER2 positive breast cancer
- Phase III Non-small cell lung cancer
- No development reported Colorectal cancer; Gastric cancer; Urogenital cancer
Most Recent Events
- 10 Dec 2024 Efficacy and adverse events data from phase III PHILA trial in HER2-positive Breast cancer presented at the 47th Annual San Antonio Breast Cancer Symposium (SABCS-2024)
- 13 Sep 2024 Efficacy and adverse event data from a phase II trial in Breast cancer presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)
- 13 Sep 2024 Efficacy and adverse event data from the phase II trial for HER2 positive Breast cancer presented at the 49th European Society for Medical Oncology Congress 2024 (ESMO-2024)