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Faricimab - Roche

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Drug Profile

Faricimab - Roche

Alternative Names: Faricimab-svoa; RG 7716; RO 6867461; Vabysmo

Latest Information Update: 11 Sep 2025

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At a glance

  • Originator Roche
  • Developer Chugai Pharmaceutical; Genentech; Roche
  • Class Bispecific antibodies; Eye disorder therapies
  • Mechanism of Action Angiopoietin-2 inhibitors; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Diabetic macular oedema; Retinal oedema; Wet age-related macular degeneration
  • Preregistration Angioid streaks
  • Phase III Choroidal neovascularisation
  • Clinical Phase Unknown Polypoidal choroidal vasculopathy

Most Recent Events

  • 11 Sep 2025 Faricimab is still in phase IIIb/IV trials for Polypoidal choroidal vasculopathy in Thailand, Taiwan, Singapore, Malaysia, South Korea, Japan, India, Hong Kong, China (Intravitreous, Injection) (ISRCTN69073386)
  • 05 Sep 2025 Pooled efficacy and safety data from the III AVONELLE-X and IIIb/IV SALWEEN trials in Wet age-related macular degeneration and Polypoidal choroidal vasculopathy released by Roche
  • 04 Sep 2025 Efficacy and safety data from the III AVONELLE-X and IIIb/IV SALWEEN trials in Wet age-related macular degeneration and Polypoidal choroidal vasculopathy released by Roche

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