Research programme: DNA repair inhibitors - Ignyta/Cancer Research Technology

Drug Profile

Research programme: DNA repair inhibitors - Ignyta/Cancer Research Technology

Alternative Names: RXDX-108; TEV-44229

Latest Information Update: 26 Jun 2018

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At a glance

  • Originator Cancer Research Technology; Teva Pharmaceutical Industries
  • Developer Cancer Research Technology; Ignyta
  • Class Small molecules
  • Mechanism of Action DNA repair inhibitors; Protein kinase C inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Cancer

Most Recent Events

  • 14 Mar 2016 Ignyta has patents pending for RXDX 108 in USA (Ignyta 10-K, March 2016)
  • 26 Feb 2016 Discontinued - Preclinical for Cancer in United Kingdom, USA (unspecified route)
  • 17 Mar 2015 Ignyta acquires RXDX 108 and other next generation atypical protein kinase C iota inhibitors from Teva Pharmaceuticals
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